Motif ID: RXR{A,B,G}.p2

Z-value: 2.807


Transcription factors associated with RXR{A,B,G}.p2:

Gene SymbolEntrez IDGene Name
RXRA 6256 retinoid X receptor, alpha
RXRB 6257 retinoid X receptor, beta
RXRG 6258 retinoid X receptor, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RXRBchr6_-_332761410.712.2e-03Click!
RXRAchr9_+_1363581340.581.9e-02Click!
RXRGchr1_-_1636809410.049.0e-01Click!


Activity profile for motif RXR{A,B,G}.p2.

activity profile for motif RXR{A,B,G}.p2


Sorted Z-values histogram for motif RXR{A,B,G}.p2

Sorted Z-values for motif RXR{A,B,G}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXR{A,B,G}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_44429748 2.557 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr19_-_1125257 2.421 SBNO2
strawberry notch homolog 2 (Drosophila)
chr7_+_2638108 2.403 NM_025250
TTYH3
tweety homolog 3 (Drosophila)
chr22_+_18081968 2.160 NM_002688
SEPT5
septin 5
chr7_+_100156358 2.106 NM_000799
EPO
erythropoietin
chr17_+_76988134 2.070 NM_001080519
BAHCC1
BAH domain and coiled-coil containing 1
chr12_+_50686990 2.070 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr19_+_55046229 1.980 PTOV1
prostate tumor overexpressed 1
chr19_+_55046088 1.977 NM_017432
PTOV1
prostate tumor overexpressed 1
chr19_-_1125201 1.963


chr7_+_2638156 1.954 TTYH3
tweety homolog 3 (Drosophila)
chr17_+_78630793 1.949 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr16_-_69277355 1.844 NM_138383
MTSS1L
metastasis suppressor 1-like
chr17_+_78286687 1.719 NM_022158
FN3K
fructosamine 3 kinase
chr19_-_1125263 1.719 NM_014963
SBNO2
strawberry notch homolog 2 (Drosophila)
chr19_+_18391211 1.715 NM_001009998
NM_032627
SSBP4

single stranded DNA binding protein 4

chr17_+_56832255 1.651 TBX2
T-box 2
chr6_-_2916786 1.648 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr17_+_56831951 1.595 NM_005994
TBX2
T-box 2
chr17_-_74433048 1.510 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr19_-_6375536 1.482 KHSRP
KH-type splicing regulatory protein
chr6_-_2916280 1.469 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr19_-_772913 1.432 NM_024888
LPPR3
lipid phosphate phosphatase-related protein type 3
chr5_+_92946348 1.419 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr9_-_101621964 1.401


chr14_-_88090641 1.386 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr19_+_18391423 1.371


chr19_-_61324456 1.368 NM_001002836
ZNF787
zinc finger protein 787
chr17_-_36475652 1.354 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr2_+_27155197 1.325 EMILIN1
elastin microfibril interfacer 1
chr11_+_440260 1.293 NM_030783
PTDSS2
phosphatidylserine synthase 2
chr11_+_65162114 1.290 NM_006747
SIPA1
signal-induced proliferation-associated 1
chr20_+_36663865 1.284 NM_001164431
ARHGAP40
Rho GTPase activating protein 40
chr15_+_39008822 1.281 NM_019074
DLL4
delta-like 4 (Drosophila)
chr4_+_995609 1.265 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr10_-_80875097 1.259 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr20_+_48032918 1.222 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr3_+_51680261 1.220 NM_001129884
NM_015926
TEX264

testis expressed 264

chr17_-_40923907 1.220 NM_014798
PLEKHM1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr6_-_132314004 1.208 NM_001901
CTGF
connective tissue growth factor
chr4_+_995395 1.202 FGFRL1
fibroblast growth factor receptor-like 1
chr19_-_772966 1.192 LPPR3
lipid phosphate phosphatase-related protein type 3
chrX_-_48929685 1.176 NM_006150
PRICKLE3
prickle homolog 3 (Drosophila)
chr16_+_658158 1.166 RHOT2
ras homolog gene family, member T2
chr12_+_55808514 1.160 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr11_+_10283171 1.151 NM_001124
ADM
adrenomedullin
chr17_-_39796649 1.146 NM_198475
FAM171A2
family with sequence similarity 171, member A2
chr6_-_33374275 1.145 RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr20_-_25514137 1.138 NM_025176
NINL
ninein-like
chr16_+_30815428 1.132 NM_001142544
NM_001330
CTF1

cardiotrophin 1

chr9_+_130224950 1.119 CERCAM
cerebral endothelial cell adhesion molecule
chr14_-_103058568 1.114 CKB
creatine kinase, brain
chr17_+_37222731 1.106 FKBP10
FK506 binding protein 10, 65 kDa
chr4_-_658035 1.101 NM_007100
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr11_+_440346 1.092 PTDSS2
phosphatidylserine synthase 2
chr11_-_86343737 1.088 FZD4
frizzled homolog 4 (Drosophila)
chr19_+_17691302 1.075 NM_018174
MAP1S
microtubule-associated protein 1S
chr5_+_149845503 1.073 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr2_-_75641587 1.071 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr19_-_6375804 1.057 KHSRP
KH-type splicing regulatory protein
chr11_+_117906965 1.035 NM_001144034
NM_001144035
NM_001144036
NM_001144037
NM_001144038
NM_032780
TMEM25





transmembrane protein 25





chr9_-_139128979 1.028 DPP7
dipeptidyl-peptidase 7
chr12_-_50502474 1.026 NM_001013690
FIGNL2
fidgetin-like 2
chr19_-_6375782 1.024 KHSRP
KH-type splicing regulatory protein
chr11_-_76059435 1.015 NM_001128922
LRRC32
leucine rich repeat containing 32
chr3_+_50281582 1.014 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr19_+_7874774 1.011 MAP2K7
mitogen-activated protein kinase kinase 7
chr20_-_2769245 1.010 NM_022760
FAM113A
family with sequence similarity 113, member A
chr19_+_447453 0.996 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr21_+_45649719 0.995


chr2_-_75641535 0.991 FAM176A
family with sequence similarity 176, member A
chr2_-_27457088 0.981 NM_144631
ZNF513
zinc finger protein 513
chr1_+_8306976 0.976 NM_001080397
SLC45A1
solute carrier family 45, member 1
chr20_-_2769120 0.975 FAM113A
family with sequence similarity 113, member A
chr17_-_36456949 0.970 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr17_+_1905104 0.965 NM_006497
HIC1
hypermethylated in cancer 1
chr19_-_18409971 0.965 NM_001170938
NM_016368
ISYNA1

inositol-3-phosphate synthase 1

chr16_-_71650034 0.960 NM_001164766
ZFHX3
zinc finger homeobox 3
chr12_-_113328271 0.957 NM_181486
TBX5
T-box 5
chr19_+_7874765 0.957 MAP2K7
mitogen-activated protein kinase kinase 7
chr12_+_50631734 0.956 ACVR1B
activin A receptor, type IB
chr2_+_27154938 0.954 NM_007046
EMILIN1
elastin microfibril interfacer 1
chr19_-_18409788 0.954 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr11_-_86343859 0.953 NM_012193
FZD4
frizzled homolog 4 (Drosophila)
chr19_-_4016467 0.936 ZBTB7A
zinc finger and BTB domain containing 7A
chr19_-_972122 0.936 NM_001033026
NM_033420
C19orf6

chromosome 19 open reading frame 6

chr20_+_21634515 0.930 PAX1
paired box 1
chr8_-_71146022 0.924 PRDM14
PR domain containing 14
chr19_-_1518875 0.919 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr11_-_66967481 0.910 CORO1B
coronin, actin binding protein, 1B
chr8_-_71146103 0.910 NM_024504
PRDM14
PR domain containing 14
chr19_-_971995 0.899 C19orf6
chromosome 19 open reading frame 6
chr11_-_45896144 0.896 NM_004813
NM_057174
PEX16

peroxisomal biogenesis factor 16

chr17_-_40923864 0.894 PLEKHM1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr20_-_43972949 0.892 PLTP
phospholipid transfer protein
chr16_-_1341766 0.878 NM_001001410
C16orf42
chromosome 16 open reading frame 42
chr19_+_7874762 0.876 MAP2K7
mitogen-activated protein kinase kinase 7
chr19_+_7874764 0.875 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr19_+_7874820 0.869 MAP2K7
mitogen-activated protein kinase kinase 7
chr21_+_46342440 0.864 NM_001849
NM_058174
NM_058175
COL6A2


collagen, type VI, alpha 2


chr20_-_33658823 0.863 FER1L4
fer-1-like 4 (C. elegans) pseudogene
chr14_+_23937766 0.862 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr7_+_100792841 0.856 NM_133457
EMID2
EMI domain containing 2
chr20_-_34925483 0.856 NM_080627
KIAA0889
KIAA0889
chr19_+_4255590 0.848 NM_024333
FSD1
fibronectin type III and SPRY domain containing 1
chr19_-_4674814 0.848 NM_139159
DPP9
dipeptidyl-peptidase 9
chr19_+_55045754 0.838 PTOV1
prostate tumor overexpressed 1
chr22_+_18085891 0.833 SEPT5
septin 5
chr20_+_21634293 0.832 NM_006192
PAX1
paired box 1
chr19_+_3045528 0.827 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr3_-_124650081 0.826 NM_183357
ADCY5
adenylate cyclase 5
chr19_-_52045890 0.822 NM_004069
NM_021575
AP2S1

adaptor-related protein complex 2, sigma 1 subunit

chr19_-_6375820 0.822 NM_003685
KHSRP
KH-type splicing regulatory protein
chr9_+_138900760 0.822 NM_021138
TRAF2
TNF receptor-associated factor 2
chr17_+_37222487 0.818 NM_021939
FKBP10
FK506 binding protein 10, 65 kDa
chr1_-_36562341 0.811 NM_018166
FAM176B
family with sequence similarity 176, member B
chr14_+_23654161 0.808 DCAF11
DDB1 and CUL4 associated factor 11
chr19_+_17047569 0.805 NM_001130065
NM_004145
MYO9B

myosin IXB

chr17_-_75808680 0.803 NM_000199
SGSH
N-sulfoglucosamine sulfohydrolase
chr21_-_32879617 0.801 NM_144659
TCP10L
t-complex 10 (mouse)-like
chr9_+_35480018 0.795 RUSC2
RUN and SH3 domain containing 2
chr3_-_49178762 0.795 CCDC71
coiled-coil domain containing 71
chr5_-_131591380 0.794 NM_001017974
NM_001142598
NM_001142599
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr8_-_93184629 0.793 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr17_+_37222726 0.792 FKBP10
FK506 binding protein 10, 65 kDa
chr17_+_7151653 0.791 EIF5A
eukaryotic translation initiation factor 5A
chr16_-_73857214 0.791 NM_001170720
NM_001170714
NM_001170718
BCAR1


breast cancer anti-estrogen resistance 1


chr3_-_49178773 0.788 NM_022903
CCDC71
coiled-coil domain containing 71
chr17_+_39620099 0.787 NM_177441
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr22_+_18085990 0.786 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chrX_-_30237403 0.783 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr19_+_38376980 0.779 LRP3
low density lipoprotein receptor-related protein 3
chr17_+_35472566 0.776 NM_001190918
NM_003250
NM_199334
THRA


thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)


chr7_+_78920846 0.774 LOC100505881
hypothetical LOC100505881
chr19_+_59064471 0.773 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr10_-_103444899 0.772 FBXW4
F-box and WD repeat domain containing 4
chr19_-_5291700 0.772 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr11_+_440408 0.771 PTDSS2
phosphatidylserine synthase 2
chr17_-_76985538 0.769


chr3_-_49178738 0.768 CCDC71
coiled-coil domain containing 71
chr20_-_33489383 0.766 NM_000557
GDF5
growth differentiation factor 5
chr19_-_4674791 0.766 DPP9
dipeptidyl-peptidase 9
chr17_+_39620108 0.764 TMUB2
transmembrane and ubiquitin-like domain containing 2
chr9_+_136673534 0.763 COL5A1
collagen, type V, alpha 1
chr9_+_35479989 0.763 NM_014806
RUSC2
RUN and SH3 domain containing 2
chr17_+_39619826 0.762 NM_001076674
NM_024107
TMUB2

transmembrane and ubiquitin-like domain containing 2

chr9_+_130222511 0.759 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr11_+_117907083 0.757 TMEM25
transmembrane protein 25
chr1_+_1233834 0.753 NM_153339
PUSL1
pseudouridylate synthase-like 1
chr17_+_35471971 0.752 NM_001190919
THRA
thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
chr19_-_63761559 0.748 UBE2M
ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
chrX_-_48929789 0.745 PRICKLE3
prickle homolog 3 (Drosophila)
chr6_-_33374678 0.743 RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr17_-_28644118 0.741 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr11_+_66381451 0.739 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr19_-_844184 0.738 MED16
mediator complex subunit 16
chr19_+_17691283 0.734 MAP1S
microtubule-associated protein 1S
chr9_+_115970599 0.733 COL27A1
collagen, type XXVII, alpha 1
chr16_+_66129481 0.732 FAM65A
family with sequence similarity 65, member A
chr19_-_6230927 0.726 NM_005934
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr19_+_2279679 0.710 SPPL2B
signal peptide peptidase-like 2B
chr20_+_2769338 0.709 NM_022575
NM_080413
VPS16

vacuolar protein sorting 16 homolog (S. cerevisiae)

chr19_-_14089560 0.708 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr1_+_9571518 0.707 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chr4_+_134292630 0.705 PCDH10
protocadherin 10
chr19_+_7874701 0.702 MAP2K7
mitogen-activated protein kinase kinase 7
chr9_-_138454071 0.701 NM_019892
INPP5E
inositol polyphosphate-5-phosphatase, 72 kDa
chr16_+_56327127 0.700 NM_005886
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr16_+_658081 0.699 NM_138769
RHOT2
ras homolog gene family, member T2
chr20_-_61933012 0.699 ZBTB46
zinc finger and BTB domain containing 46
chr11_+_66381077 0.697 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr9_-_16860664 0.694 BNC2
basonuclin 2
chr19_+_3457264 0.693 NM_016263
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr9_-_130573671 0.689 ZER1
zer-1 homolog (C. elegans)
chr19_+_47480445 0.689 NM_015125
CIC
capicua homolog (Drosophila)
chr19_+_45664889 0.688 NM_020971
SPTBN4
spectrin, beta, non-erythrocytic 4
chr9_+_115678365 0.686 NM_133374
ZNF618
zinc finger protein 618
chr1_-_153213483 0.686 NM_001130041
NM_003029
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr22_+_18485095 0.682 RANBP1
RAN binding protein 1
chr16_-_11257539 0.680 NM_003745
SOCS1
suppressor of cytokine signaling 1
chr1_-_32460526 0.678 TMEM234
transmembrane protein 234
chr20_-_43972982 0.678 PLTP
phospholipid transfer protein
chr9_+_130942029 0.676 PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr17_-_7061641 0.676 NM_001128827
DLG4
discs, large homolog 4 (Drosophila)
chr17_-_23716391 0.676 NM_001080837
SEBOX
SEBOX homeobox
chr14_+_76298693 0.672 VASH1
vasohibin 1
chr5_-_149809424 0.671 RPS14
ribosomal protein S14
chr17_-_74432671 0.670 TIMP2
TIMP metallopeptidase inhibitor 2
chr16_+_56327168 0.670 KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr11_+_47227009 0.668 NM_001130102
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr19_+_59064795 0.668 MYADM
myeloid-associated differentiation marker
chr9_-_139128777 0.666 DPP7
dipeptidyl-peptidase 7
chr17_-_37221976 0.662 NM_006455
LEPREL4
leprecan-like 4
chr14_+_22375632 0.662 NM_004995
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr16_+_68705714 0.661 PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr9_-_109291575 0.660 KLF4
Kruppel-like factor 4 (gut)
chr14_-_60260211 0.659 NM_017420
SIX4
SIX homeobox 4
chr19_+_54723044 0.655 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr7_-_75461897 0.653 NM_031925
TMEM120A
transmembrane protein 120A
chr3_-_48647811 0.653 SLC26A6
solute carrier family 26, member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 2.26e-06 GO:0009653 anatomical structure morphogenesis
1.55 3.88e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.26 3.51e-05 GO:0048856 anatomical structure development
1.28 4.03e-05 GO:0048731 system development
1.76 4.07e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.40 5.11e-05 GO:0007399 nervous system development
1.13 5.15e-05 GO:0065007 biological regulation
1.31 5.88e-05 GO:0048519 negative regulation of biological process
1.15 6.45e-05 GO:0050794 regulation of cellular process
1.64 1.50e-04 GO:0010629 negative regulation of gene expression
1.27 1.67e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61 1.76e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.40 1.79e-04 GO:0009966 regulation of signal transduction
1.28 1.99e-04 GO:0010468 regulation of gene expression
1.13 2.01e-04 GO:0050789 regulation of biological process
1.67 2.06e-04 GO:0051253 negative regulation of RNA metabolic process
1.36 2.23e-04 GO:0023051 regulation of signaling
1.67 2.54e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.26 2.70e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.61 2.74e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.28 3.33e-04 GO:0048522 positive regulation of cellular process
1.26 3.78e-04 GO:0048518 positive regulation of biological process
1.58 4.52e-04 GO:0010628 positive regulation of gene expression
1.30 4.73e-04 GO:0048523 negative regulation of cellular process
1.28 5.41e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.29 5.63e-04 GO:0051252 regulation of RNA metabolic process
1.53 8.59e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.58 9.98e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.59 1.02e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 1.06e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.25 1.15e-03 GO:0009889 regulation of biosynthetic process
1.25 1.22e-03 GO:0031326 regulation of cellular biosynthetic process
1.30 1.27e-03 GO:0030154 cell differentiation
1.21 1.38e-03 GO:0080090 regulation of primary metabolic process
1.29 1.54e-03 GO:0048869 cellular developmental process
1.20 1.54e-03 GO:0032502 developmental process
1.47 1.58e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.28 1.61e-03 GO:0006355 regulation of transcription, DNA-dependent
1.26 1.63e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.31 1.67e-03 GO:0048583 regulation of response to stimulus
1.54 1.93e-03 GO:0009890 negative regulation of biosynthetic process
1.08 1.99e-03 GO:0009987 cellular process
1.57 1.99e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.22 2.08e-03 GO:0060255 regulation of macromolecule metabolic process
1.21 2.26e-03 GO:0007275 multicellular organismal development
1.21 2.53e-03 GO:0031323 regulation of cellular metabolic process
1.64 4.04e-03 GO:0072358 cardiovascular system development
1.64 4.04e-03 GO:0072359 circulatory system development
2.53 4.31e-03 GO:0030326 embryonic limb morphogenesis
2.53 4.31e-03 GO:0035113 embryonic appendage morphogenesis
1.53 4.34e-03 GO:0051254 positive regulation of RNA metabolic process
1.46 4.62e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.46 4.67e-03 GO:0009891 positive regulation of biosynthetic process
2.36 6.55e-03 GO:0048736 appendage development
2.36 6.55e-03 GO:0060173 limb development
1.19 6.73e-03 GO:0019222 regulation of metabolic process
1.94 6.88e-03 GO:0048514 blood vessel morphogenesis
1.84 7.47e-03 GO:0001568 blood vessel development
2.38 7.98e-03 GO:0035107 appendage morphogenesis
2.38 7.98e-03 GO:0035108 limb morphogenesis
1.46 1.26e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.36 1.76e-02 GO:0031325 positive regulation of cellular metabolic process
1.40 1.84e-02 GO:0009892 negative regulation of metabolic process
1.36 2.04e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.41 2.79e-02 GO:0022008 neurogenesis
1.71 2.82e-02 GO:0060284 regulation of cell development
1.45 2.90e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41 4.01e-02 GO:0048699 generation of neurons
1.74 4.13e-02 GO:0001944 vasculature development
1.33 4.43e-02 GO:0009893 positive regulation of metabolic process
1.46 4.65e-02 GO:0009790 embryo development
1.33 4.87e-02 GO:0051239 regulation of multicellular organismal process
1.40 4.98e-02 GO:0031324 negative regulation of cellular metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 1.50e-04 GO:0005622 intracellular
1.08 2.50e-04 GO:0044424 intracellular part
1.71 3.24e-03 GO:0005773 vacuole
1.75 6.28e-03 GO:0000323 lytic vacuole
1.75 6.28e-03 GO:0005764 lysosome
1.08 7.02e-03 GO:0043226 organelle
1.08 8.53e-03 GO:0043229 intracellular organelle
1.09 1.07e-02 GO:0005737 cytoplasm
1.57 1.51e-02 GO:0043005 neuron projection
1.03 1.85e-02 GO:0044464 cell part
1.03 1.92e-02 GO:0005623 cell
2.44 2.35e-02 GO:0005604 basement membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.50e-08 GO:0005515 protein binding
1.66 5.20e-07 GO:0043565 sequence-specific DNA binding
1.52 1.27e-06 GO:0030528 transcription regulator activity
1.52 2.37e-06 GO:0001071 nucleic acid binding transcription factor activity
1.52 2.37e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.08 1.16e-05 GO:0005488 binding
1.28 7.59e-05 GO:0003677 DNA binding
2.00 5.33e-04 GO:0000975 regulatory region DNA binding
2.00 5.33e-04 GO:0001067 regulatory region nucleic acid binding
2.00 5.33e-04 GO:0044212 transcription regulatory region DNA binding
1.75 1.47e-03 GO:0016563 transcription activator activity
1.96 2.00e-03 GO:0010843 promoter binding
1.54 2.92e-02 GO:0019904 protein domain specific binding
1.62 4.10e-02 GO:0003779 actin binding